In Downtown Florence:

Gunrunner Boutique

Address: 310 N Court St, Florence, AL 35630
Located in the heart of downtown Florence, Alabama, the GunRunner features 10 spacious luxury suites that are uniquely designed to celebrate the world-class music, fashion, art, and history of the Shoals area.
Phone: (256) 349-5464)
Price per room (avg) 179 per night

The Stricklin Hotel

Address: 317 N Court St, Florence, AL 35630
Just a 3-minute walk from Wilson Park, this informal hotel set in the top 2 floors of a building that also houses a restaurant (breakfast only), and a vintage bowling area with a bar.  4 star hotel.
Phone: (256) 248-9982
Price per room (avg) 129 per night.

Days Inn – By Wyndham 
400 S Ct St, Florence, AL 35630
Unfussy rooms in a modest hotel with a seasonal outdoor pool, plus free Wi-Fi & breakfast.  3 Star Hotel
Phone(256) 760-8888
Price per room $75 for two
Hampton Inn and Suites

505 S Court StFlorence, AL 35630  Cross Streets: Near the intersection of S Court St and E Limestone St/W Limestone St
(256) 767-8282

Outside of the Downtown Area

Mariott Hotel & Spa– 

10 Hightower Pl, Florence, AL 35630,
River-view property with a revolving restaurant & bar with live music, plus indoor & outdoor pools. 4 star HotePhone(256) 246-3600Price per room $189 for two (special Pricing for the Renaissance may apply)

Holiday Inn Express & Suites

180 Etta Gray St, Florence, AL
(256) 246-2200

Baymont Inn and Suites- Florence/Muscle Shoals

115 Ana Drive  Florence, Al
(256) 764-5326

Comfort Suites

140 Matthew Paul Court  Florence, AL
(256) 247-2300

Quality Inn

150 Etta Gray Street  Florence, AL
(256) 740-0444

Hampton Inn 

2281 Florence Blvd, Florence, AL 35630 Contemporary hotel with free Wi-Fi, breakfast & parking, plus a pool & a business center.  3 star hotel
(256) 764-8888
Price per room $109 for two  ( special Pricing for the Renaissance may apply)